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Antibiotic Resistance

Infectious Disease Epidemiology Section Office of Public Health Louisiana Dept of Health Hospitals …Your Taxes at Work…
Brief History of Resistance
Antibiotic Failures are NOT all due to Resistance
Lack of effectiveness in vivo may not be due to bacterial resistance the antibiotic may not able to reach the microorganisms cannot go through blood brain barrier be too toxic at doses required to be effective against targeted microorganisms …
Antibiotics Use Promotes Resistance
Resistance Seems to Develop Mostly in the Hospitals
Archibald L1997.Antimicrobial resistance in isolates from inpatients and outpatients in the United States increasing importance of the intensive care unit. Clinical Infectious Diseases. 24(2)211-215
Sustained Antibiotic Use Contributes to Resistance
Resistance Seems to Develop Mostly in ICU
Project ICARE (Intensive Care Antibiotic Resistance Epidemiology) by CDC and Emory U SPH to collect data

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