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History of Anesthesia Methods of Administration Mechanisms of Action Companion Animal Drugs
Amnesia Loss of memory Immobility Stay still Analgesia Pain relief Homeostasis
Blaze ppt. TCSVM
Common Inhalation Intravenous Intramuscular Less Common Rectal Oral Nasal Intraperitoneal
Used to think all anesthetics worked the same way The gas disrupted cell membrane lipids Flaw enantiomers of the same anesthetic have unique actions but the same physical properties (i.e. isoflurane) Therefore, anesthetics must bind to specific proteins
Hyperpolarize neurons Anticholingeric suppresses nervous system communication Alpha-2 adrenergic receptor agonist/antagonist suppress norepinephrine binding/release to receptor Cardiovascular depressant Respiratory depressant
Ach is a main neurotransmitter of the autonomic NS of PNS In the CNS, excitatory actions
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Diethyl ether, nit
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