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Basic Pathway
Lymphocytes and Lymphoid Tissues
Components of the Immune System
I. Bone Marrow – Hematopoietic Stem Cells Myeloid progenitor neutrophils -macrophage basophils – mast cells eosinophils Common lymphoid progenitor T-lymphocytes B-lymphocytes
Hematopoiesis
Hematopoiesis is driven by cytokines stem cell factor IL GM-CSF G-CSF M-CSF IL-7 IL-11
Hematopoiesis
Erythrocyte-stimulated by EPO (Amgen) EPO erythropoietin Megakaryocyte/Platelets-stimulated by IL-11 Granulocyte/Monocyte-stimulated by GM-CSF, G-CSF, and M-CSF Lymphocyte -stimulated by IL-7
Lymphocyte Maturation
Stem Cell Nave or virgin lymphocytes migrate to secondary lymphoid organs (short lived) Activation Memory-Effector cells
Thymus
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Category : Immunology