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Therapeutic use of botulinum toxin
FDA approved for neuromuscular disorders
Blepharospasm
Strabismus
Torticollis
Many other unapproved uses
Packaged in dilute preparations
Not feasible to use licensed toxin for weapon
Bioweapon Potential
Botulinum toxin a major threat because
Extreme potency and lethality
Ease of production
Ease of transport
Need for prolonged intensive care
Top 6 potential biological warfare agents
Listed as Category A agent High priority
Bioweapon Potential
Estimated Effect
Most toxic substance known
1 gram crystalline toxin can kill 1 million people if dispersed and inhaled evenly
Point source aerosol release
Incapacitate/kill 10 of people downwind within 500 meters
Bioweapon Potential
Naturally occurring botulism
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Category : General Health