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PPT : Summer 2008 Workshop in Biology and Multimedia for High School Teachers

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* infectious agent: Streptococcus pyogenes
– spherical bacteria usually found in pairs or chains
* most sore throats are actually caused by viruses and are NOT considered strep throat (~15-35% are strep throat) en.wikipedia.org/wiki/Strep_throat
* symptoms: sudden, severe sore throat, fever over 101°F, swollen tonsils and lymph nodes, white or yellow spots on the back of a bright red throat
* transmission usually by air-born bacteria
* incubation period prior to symptoms 2-5 days

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of Harvard College.
Sample Bacterial Illness: Strep Throat en.wikipedia.org/wiki/Strep_throat
* diagnosed with a throat culture and detection of strep-specific molecules
* treated with antibiotics, usually penicillin for 10 days

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of Harvard College.
Viral Illness: The Common Cold
* symptoms: sore throat, runny nose, nasal congestion, cough
* prevalance: 3 colds/ person/ year
* incubation period 2-5 days
* no cure for the common cold (or the flu)

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of Harvard College.
Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of Harvard College.
Should you ask for an antibiotic when you have a cold or the flu?
To understand why antibiotics DO NOT work for viruses, you should understand:
* how antibiotics work
* basic structural properties of bacteria and viruses
* basic biosynthetic pathways of bacteria and viruses

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of Harvard College.
Structure of a Bacterial Cell
-maintains cell structure
-composed of peptidoglycan, a polymer of sugars and amino acids
-phospholipid bilayer surrounding cell
-contains proteins that play a role in transport of ions, nutrients, and wastes
-tail-like structure used for locomotion

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