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PPT : Treatment Wound Botulism

Botulism
Manav Bhavsar
Introduction
Clostridium botulinum
Form spores in anaerobic, non acidic Ph
Modern industrial canning develop kill spores
Toxins sensitive to temp all killed 850C 5min
Human intestine not conductive germination
Exceptions are infants adult toxemia cases

Food Borne Botulism
Wound Botulism
Clinical Features
Gastrointestinal Symptoms
Neurological Symptoms
Onset
Onset of GI and neurological symptoms may be between 6 hours and 8 days
If onset is very rapid, there may be no symptoms before sudden respiratory paralysis occurs
Differential Diagnosis
Investigations
Treatment
Loss of the protective gag reflex intubation and mechanical ventilation
Antitoxin
Antibiotics
Isolation not necessary except inhalational strongly

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