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PPT : Trends and burden of antimicrobial resistance in the European Union

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* Prevention and control of AMR can be achieved by:
o Prudent use of existing of antimicrobial agents
o Good hygiene practices (infection control)
o Novel antimicrobial agents active on resistant bacteria
* Need to ascertain the perceived gap between:
o infections due to resistant bacteria
o development of novel agents aimed at treating such infections

Antimicrobial resistance (AMR) is still a growing European and global health problem.
(Council Conclusions on Antimicrobial Resistance (AMR), Luxembourg, 10 June 2008)
Background for ECDC-EMEA Joint Report
o To produce a report on “the gap between the increasing prevalence of multidrug-resistant bacteria and antibacterial drug development aimed at treating such infections”
* Composition
o ECDC appointed experts
o EMEA appointed experts
o ECDC and EMEA staff
o Co-opted experts, e.g. from ReAct
o Observers: European Commission, ESCMID

ECDC-EMEA Joint Working Group (established February 2008)
* Based on the most frequent bacteria responsible for bloodstream infections
* Certain resistances were used as indicators for multidrug resistance (resistance to multiple antibiotics)
* 6 most frequent resistant bacteria:
Gram-positive-bacteria

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PPT : Trends and burden of antimicrobial resistance in the European Union Category : Antibiotics
Source : www.ecdc.europa.eu
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