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Smallpox

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Variola
Overview
Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control
The Organism
The Organism
Double stranded DNA Orthopoxvirus Variola, cowpox, vaccinia, monkeypox, Variola major or minor Stable out side host Retains infectivity Last case, 1977 Eradicated, 1980
History
History of Smallpox
First appeared in Northeastern Africa around 10,000 BC Skin lesions on mummies 1570-1085 BC Ramses V
History of Smallpox
1763, Sir Jeffrey Amherst Smallpox in blankets for Indians 18th century Europe 400,000 deaths Case fatality, 20-60 Scars, blindness Infants, 80-98 CF

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Smallpox Category : Public Education
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